Search on: GUANINE NUCLEOTIDE EXCHANGE FACTORS 
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Descriptor English:   Guanine Nucleotide Exchange Factors 
Descriptor Spanish:   Factores de Intercambio de Guanina Nucleótido 
Descriptor Portuguese:   Fatores de Troca do Nucleotídeo Guanina 
Synonyms English:   Guanine Nucleotide Releasing Factors
GDP Exchange Factors
GDP-GTP Reversing Factors  
Tree Number:   D12.644.360.325.300
D12.776.402.300
D12.776.476.325.300
Definition English:   Protein factors that promote the exchange of GTP for GDP bound to GTP-BINDING PROTEINS. 
History Note English:   2000; use GUANINE NUCLEOTIDE EXCHANGE FACTORS (NM) 1978-1999; for GDP-GTP EXCHANGE PROTEIN use RAB3 GTP-BINDING PROTEINS (NM) 1994-1999; for GDP DISSOCIATION FACTOR use RAP GTP-BINDING PROTEINS (NM) 1996-1999 
Allowable Qualifiers English:  
administration & dosage adverse effects
agonists antagonists & inhibitors
analysis biosynthesis
blood cerebrospinal fluid
chemistry classification
chemical synthesis contraindications
drug effects deficiency
diagnostic use economics
genetics history
immunology isolation & purification
metabolism pharmacology
physiology pharmacokinetics
poisoning radiation effects
supply & distribution secretion
standards toxicity
therapeutic use ultrastructure
urine  
Record Number:   34489 
Unique Identifier:   D020662 

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